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https://hdl.handle.net/20.500.12955/1143
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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Tauchen, Jan | - |
dc.contributor.author | Bortl, Ludvik | - |
dc.contributor.author | Huml, Lukas | - |
dc.contributor.author | Miksatkova, Petra | - |
dc.contributor.author | Doskocil, Ivo | - |
dc.contributor.author | Marsik, Petr | - |
dc.contributor.author | Panduro Villegas, Pablo Pedro | - |
dc.contributor.author | Bendezu Flores, Ymber | - |
dc.contributor.author | Van Damme, Patrick | - |
dc.contributor.author | Lojka, Bohdan | - |
dc.contributor.author | Havlik, Jaroslav | - |
dc.contributor.author | Lapcik, Oldrich | - |
dc.contributor.author | Kokoska, Ladislav | - |
dc.coverage.spatial | Perú | es_PE |
dc.date.accessioned | 2020-10-03T01:22:17Z | - |
dc.date.available | 2020-10-03T01:22:17Z | - |
dc.date.issued | 2016-06-14 | - |
dc.identifier.citation | Tauchen, J.; Bortl, L.; Huml, L.; Miksatkova, P.; Doskocil, I.; Marsik, P.; Panduro, P.; Bendezu, Y.; Van Damme, P.; Lojka, B.; Havlik, J.; Lapcik, O.; Kokoska, L. (2016). Phenolic composition, antioxidant and anti-proliferative activities of edible and medicinal plants from the Peruvian Amazon. Revista Brasileira de Farmacognosia Volume 26, Issue 6, Pages 728-737. doi: 10.1016/j.bjp.2016.03.016 | es_PE |
dc.identifier.uri | http://repositorio.inia.gob.pe/handle/20.500.12955/1143 | - |
dc.description.abstract | Among 23 extracts of medicinal and edible plants tested, Mauritia flexuosa L.f., Arecaceae, showed significant antioxidant ability (DPPH and ORAC = 1062.9 and 645.9 ± 51.4 μg TE/mg extract, respectively), while Annona montana Macfad., Annonaceae, demonstrated the most promising anti-proliferative effect (IC50 for Hep-G2 and HT-29 = 2.7 and 9.0 μg/ml, respectively). However, combinatory antioxidant/anti-proliferative effect was only detected in Oenocarpus bataua Mart., Arecaceae (DPPH = 903.8 and ORAC = 1024 μg TE/mg extract; IC50 for Hep-G2 and HT-29 at 102.6 and 38.8 μg/ml, respectively) and Inga edulis Mart., Fabaceae (DPPH = 337.0 and ORAC = 795.7 μg TE/mg extract; IC50 for Hep-G2 and HT-29 at 36.3 and 57.9 μg/ml, respectively). Phenolic content was positively correlated with antioxidant potential, however not with anti-proliferative effect. None of these extracts possessed toxicity towards normal foetal lung cells, suggesting their possible use in development of novel plant-based agents with preventive and/or therapeutic action against oxidative stress-related diseases. | es_PE |
dc.description.tableofcontents | Introduction. Materials and methods. Results. Discussion. Conclusion. References. | es_PE |
dc.format | application/pdf | es_PE |
dc.language.iso | eng | es_PE |
dc.publisher | El Sevier | es_PE |
dc.relation.ispartof | Revista Brasileira de Farmacognosia Volume 26, Issue 6, November–December 2016, Pages 728-737 | es_PE |
dc.rights | info:eu-repo/semantics/openAccess | es_PE |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | es_PE |
dc.source | Instituto Nacional de Innovación Agraria | es_PE |
dc.source.uri | Repositorio Institucional - INIA | es_PE |
dc.subject | Antioxidant | es_PE |
dc.subject | Anticarcinogenic | es_PE |
dc.subject | Phenolic compounds | es_PE |
dc.subject | Plant extracts | es_PE |
dc.title | Phenolic composition, antioxidant and anti-proliferative activities of edible and medicinal plants from the Peruvian Amazon | es_PE |
dc.type | info:eu-repo/semantics/article | es_PE |
dc.subject.ocde | Biotecnología agrícola, Biotecnología alimentaria | es_PE |
dc.identifier.journal | Revista Brasileira de Farmacognosia | es_PE |
dc.relation.publisherversion | http://dx.doi.org/10.1016/j.bjp.2016.03.016 | es_PE |
dc.publisher.country | Brasil | es_PE |
dc.identifier.doi | http://dx.doi.org/10.1016/j.bjp.2016.03.016 | - |
Aparece en las colecciones: | Artículos científicos |
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Tauchen-et-el_2016_Antioxidant_Anti-proliferative.pdf | 552,08 kB | Adobe PDF | Visualizar/Abrir |
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