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dc.contributor.authorCastro Gómez, Juan Carlos-
dc.contributor.authorMaddox, J. Dylan-
dc.contributor.authorCobos Ruiz, Marianela-
dc.contributor.authorParedes, Jae D.-
dc.contributor.authorMarapara del Aguila, Jorge Luis-
dc.contributor.authorBraga, Janeth-
dc.contributor.authorImán Correa, Sixto Alfredo-
dc.contributor.authorRodríguez, Hicler N.-
dc.contributor.authorCastro, Carlos G.-
dc.identifier.citationCastro J.C. et al. (2020) Bioactive Compounds of Camu-Camu (Myrciaria dubia (Kunth) McVaugh). In: Murthy H., Bapat V. (eds) Bioactive Compounds in Underutilized Fruits and Nuts. Reference Series in Phytochemistry. Springer, Chames_PE
dc.description.abstractCamu-camu is a shrub, native to the Amazon that thrives in areas where flooding is frequent. Genetically, the plant is characterized by a diploid genome and moderate genetic diversity. Several parts of the plant are used in traditional folk medicine to treat a variety of acute and chronic diseases. For over 50 years, the exceptionally high vitamin C content of camu-camu has attracted worldwide attention that continues today because of the recent discovery of several health-promoting phytochemicals with corroborated biological activities (e.g., antioxidant, anti-obesity, antidiabetic). All of these beneficial attributes are well supported by in vitro and in vivo studies as well as human clinical trials. The metabolic precursors of these phytochemicals are synthesized in key metabolic pathways (i.e., the shikimate pathway, the mevalonate pathway). Of these metabolic pathways, we show details for the biosynthesis of betulinic acid, trans-resveratrol, and syringic acid. In conclusion, camu-camu is an exceptional plant for its ability to produce and accumulate significant amounts of a variety of health-promoting phytochemicals. Although several metabolic pathways responsible for the biosynthesis of these phytochemicals have been reconstructed based on fruit and seedling transcriptomes, detailed knowledge of the vast majority of metabolic pathways and their molecular regulatory mechanisms is lacking. Consequently, we must increase our knowledge of the metabolic processes using multi-omic approaches so that we can acquire the skills necessary to develop genetically improved varieties of camu-camu and implement biotechnological applications for the production of these bioactive phytochemicals.es_PE
dc.publisherHosakatte Niranjana Murthyes_PE
dc.relation.ispartofBioactive Compounds in Underutilized Fruits and Nuts pp 1-25es_PE
dc.relation.ispartofseriesReference Series in Phytochemistryen
dc.sourceInstituto Nacional de Innovación Agrariaes_PE
dc.source.uriRepositorio Institucional - INIAes_PE
dc.subjectBioactive compoundses_PE
dc.subjectBiosynthetic pathwayses_PE
dc.titleBioactive Compounds of Camu-Camu (Myrciaria dubia (Kunth) McVaugh)en
dc.subject.ocdeBiotecnología agrícolaes_PE
dc.subject.ocdeBiotecnología alimentariaes_PE
dc.identifier.journalSpringer Nature Switzerland AGes_PE
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