Examinando por Autor "Rojas Cruz, Diórman"

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Genomic characterization of Escherichia coli isolates from alpaca crias (Vicugna pacos) in the peruvian highlands: insights into functional diversity and pathogenicity
(MDPI, 2025-06-30) Zapata, Celso; Rodriguez Perez, Lila Maciel; Romero Avila, Yolanda Madedein; Coila, Pedro; Hañari Quispe, Renán Dilton; Oros, Oscar; Zanabria, Víctor; Quilcate Pairazaman, Carlos Enrique; Rojas Cruz, Diórman; Cruz Luis, Juancarlos Alejandro; Ortiz Morera, Narda Cecilia; Estrada Cañari, Richard
Diarrhea in alpaca crias significantly impacts livestock health in high-altitude regions, with Escherichia coli as a common pathogen. This study analyzed 10 E. coli isolates from diarrheic and healthy alpacas using whole-genome sequencing to assess genetic diversity, virulence factors, and antibiotic resistance. Predominant sequence types (ST73, ST29), serotypes (O22:H1, O109:H11), and phylogroups (B2, B1, A) were identified. Virulence profiling revealed ExPEC-like and EPEC pathotypes, while resistance genes for β-lactams (blaEC-15), fosfomycin (glpT_E448K), and colistin (pmrB) were prevalent. These findings highlight the need for genomic surveillance and antimicrobial stewardship to manage E. coli infections in alpacas and reduce public health risks.